Effect of a 24 week home-based walking program on the incidence of aromatase inhibitor induced musculoskeletal pain: The WISE prospective, randomized, multicenter trial [SAKK 95/17]

Background: Aromatase inhibitor (AI) induced arthralgia/myalgia (AIA) is a frequent side-effect of AI-therapy. We investigated the effect of a simple, home-based walking program outdoors, beginning at the start of AI-therapy, on the incidence of AIA, as well as symptom burden and quality of life (QoL) during 24 weeks.