PI3K/AKT/mTOR通路
蛋白激酶B
MAPK/ERK通路
串扰
刺猬信号通路
生物
RPTOR公司
效应器
癌症研究
细胞生物学
信号转导
光学
物理
作者
Tülin Erşahin,Nurcan Tunçbağ,Rengül Çetin-Atalay
出处
期刊:Molecular BioSystems
[The Royal Society of Chemistry]
日期:2015-01-01
卷期号:11 (7): 1946-1954
被引量:479
摘要
The phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of the rapamycin (mTOR) signalling pathway is hyperactivated or altered in many cancer types and regulates a broad range of cellular processes including survival, proliferation, growth, metabolism, angiogenesis and metastasis.
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