[Evolution of clinical outcomes following hepatitis C virus clearance].

As hepatitis C treatment entered the era of direct-acting antiviral drugs, an increasing number of patients received treatment and achieved virus clearance, but virus clearance is merely a relative endpoint. Future emphasis will be placed on post-treatment benefits and the evolution of clinical outcomes. This article aims to describe the improvement in all-cause mortality and hepatic and extrahepatic-related diseases following virus clearance, particularly in patients treated with direct-acting antiviral drugs.随着丙型肝炎的治疗进入直接抗病毒药物时代，获得治疗并实现病毒清除的患者越来越多，但病毒清除只是一个相对终点，治疗后的获益和临床结局演变将是今后关注的一个重点，现描述病毒清除后尤其是直接抗病毒药物治疗的患者全因死亡，肝病及肝外相关疾病的改善情况。.