Suzuki–Miyaura Coupling Reaction by PdII‐Catalyzed Aromatic CH Bond Activation Directed by an N‐Alkyl Acetamino Group

A seamless join: An efficient method to construct a C(sp2)C(sp2) bond has been developed by using a Suzuki–Miyaura-type coupling of N-alkyl acetanilides with boronic acids. The reaction was catalyzed by a PdII species and the CH bond activation was directed by the acetamino group (see scheme). This reaction offers a halogen-free method to construct complicated structures.