医学
膜内骨化
异位骨化
结缔组织病
骨化
结缔组织
病理
间充质干细胞
解剖
出处
期刊:PubMed
日期:1995-08-01
卷期号: (317): 243-5
被引量:16
摘要
Progressive osseous heteroplasia is a rare developmental disorder of mesenchymal differentiation characterized by cutaneous osteomas in infancy and by progressive heterotopic intramembranous ossification of skin and deep connective tissue. To date, typical features of the disorder have been reported only in 8 female patients. This report documents progressive osseous heteroplasia in 2 boys and has important implications for the clinical detection and pathogenetic understanding of this rare disorder.
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