Force-dependent rapid immunoassay of high specificity and sensitivity
免疫分析
灵敏度(控制系统)
医学
抗体
免疫学
工程类
电子工程
作者
Xiaodan Zhao,Yanqige Jiang,Yu Zhou,Jie Yan
标识
DOI:10.1016/j.mbm.2024.100061
摘要
The significance of early detection and isolation of infected individuals, along with the quantitative assessment of antibodies against the virus, has gained widespread recognition during the ongoing covid-19 pandemic. This necessitates the development of cost-effective, user-friendly, decentralized testing methods characterized by both high sensitivity and specificity. In this article, we present a comprehensive review of an innovative, low-cost rapid decentralized immunoassay technology, applicable across various diagnostic and quantitative testing scenarios. Distinguishing itself from conventional immunoassay technologies, this method is featured with mechanically enhanced specificity without compromising sensitivity. We delve into the basic principle of the technology and a comparative analysis of this technology in relation to other immunodiagnostic methods, highlighting its potential applications in a wide spectrum of diagnostic tests.