吞咽
吞咽困难
冲程(发动机)
医学
脑干
改良兰金量表
脑功能偏侧化
物理医学与康复
麻醉
心脏病学
内科学
物理疗法
听力学
外科
缺血性中风
缺血
工程类
机械工程
作者
Xiancong Ma,Yang Peng,Lida Zhong,Fang Li,Z Tang,Xiao Bao,Jingjun Chen
标识
DOI:10.1016/j.brainresbull.2024.110880
摘要
Strokes will result in decreased in cortical excitability and changed in the balance between the affected and unaffected hemispheres. Previous studies have focused on cortical changes in healthy subjects during swallowing, while they remain unknown in patients with stroke at different locations. Thus, the purpose of this study was to research cortical activation patterns of swallowing in patients with dysphagia and healthy subjects by the functional near-infrared spectroscopy (fNIRS). We also focus on the comparability of brain activation areas associated with swallowing between patients with different stroke locations and healthy subjects. total of 104 participants were invited to our study, involving 86 patients with dysphagic unilateral hemispheric stroke and 18 age and sex matched healthy controls. The stroke patients were categorized into patients with left unilateral stroke lesions (n=30), patients with right unilateral stroke lesions (n=32) and patients with brainstem injury (n=24) according to different stroke sites. All patients underwent a series of clinical swallowing function assessments, such as the Fiberoptic endoscopic dysphagia severity scale (FEDSS), penetration-aspiration scale (PAS) of Rosenbek, the gugging swallowing screen (GUSS) and the functional oral Intake scale (FOIS) after informed consent has been signed. All participants received the fNIRS system assessment. The results showed that extensive areas of the cerebral cortex activated during the swallowing tasks in healthy participants (P
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