Betti base derived P-stereogenic phosphine-diamidophosphite ligands with a single atom spacer and their application in asymmetric catalysis

Small bite-angle P -chirogenic PNP ligands have been synthesized stereo-selectively and employed in Rh-catalyzed asymmetric hydrogenation and Pd-catalyzed asymmetric allylic substitution resulting in moderate to excellent enantioselectivities.