[The efficiency of 23 G vitrectomy combined with preoperative subtenon injection of triamcinolone acetonide for treatment of retinal detachment associated with choroidal detachment].

医学 玻璃体切除术 视网膜脱离 曲安奈德 眼压 眼科 视力 丙酮 地塞米松 视网膜 外科 内科学
作者
Jianbo Mao,Shih Chi Wu,Y Q Chen,Ying-Li Dong,Bin Zheng,Jiwei Tao,S X Zhao,Fangyuan Dong,Lijun Shen
出处
期刊:PubMed 卷期号:54 (4): 252-257 被引量:2
标识
DOI:10.3760/cma.j.issn.0412-4081.2018.04.005
摘要

Objective: To evaluate the efficiency of 23 G vitrectomy combined with preoperative subtenon injecfion of triamcinolone acetonide for treatment of rhegmatogenous retinal detachment associated with choroidal detachment. Methods: A retrospective analysis. Forty-eight (16 males and 32 females, aged 57.3±13.9) consecutive patients (48 eyes) who were diagnosed with rhegmatogenous retinal detachment associated with choroidal detachment and received 23 G vitrectomy at the Eye Hospital of Wenzhou Medical University during January 2012 and January 2015 were enrolled. Twenty-three eyes were treated with subtenon injection TA 5 d before the planned 23 G vitrectomy (TA group). Twenty-five eyes were treated with dexamethasone 3 to 5 d before the planned vitrectomy (Dex group). Type-B ultrasonic, intraocular pressure, best corrected visual acuity examinations were conducted for all eyes on admission day, preoperatively and at 1 month, 3 month postoperatively, and during the last visit. The rate of reattachment, change of height of choroidal detachment, intraocular pressure, best corrected visual acuity, and the complication of the eyes between the two groups were compared. All patients were followed up at least half a year after the repair surgery. Results: The intraocular pressure of the TA group was higher than the Dex group[(8.58±3.83)mmHg vs. (6.70±2.49)mmHg (1 mmHg=0.133 kPa), (t=2.032)], and the height of choroidal detachment was lower in TA group [0.90(0.00, 3.84)mm vs. 4.03(1.05, 5.38)mm, Z=-2.569, P<0.05]. There is no statistic difference between the reattachment rate of the two groups [95.7%(22/23) vs. 76.0%(19/25), χ(2)=2.304, P=0.129], but it seems it was better in TA group. The best corrected visual acuity results of the last visit was better in TA group than Dex group [(0.91±0.54) vs. (1.25±0.62), t=-2.034, P=0.048]. The rate of hypertention was higher in TA group than Dex group at 1 month, 3 month postoperatively(χ(2)=2.304, 5.648, P<0.05), while there was no statistic difference of hypertention rate during last visit between the two groups (χ(2)=0.006, P=0.941). Conclusions: The treatment of 23 G vitrectomy combined with subtenon injection of triamcinolone acetonide can improve the intraocular pressure, reduce the height of choroidal detachment, and improve the best corrected visual acuity after the surgery, but it may cause heyertenion. (Chin J Ophthalmol, 2018, 54: 252-257).目的: 探讨后Tenon囊下注射曲安奈德后行23 G玻璃体切除术治疗脉络膜脱离型视网膜脱离的疗效。 方法: 回顾性病例对照研究。收集2012年1月至2015年1月在温州医科大学附属眼视光医院确诊为脉络膜脱离型视网膜脱离并接受23 G玻璃体切除术治疗的连续性病例48例(48只眼),其中男性16例(16只眼),女性32例(32只眼),平均年龄为(57.3±13.9)岁。23只眼术前后Tenon囊下注射曲安奈德(曲安奈德组),25只眼术前静脉滴注地塞米松10 mg/d(地塞米松组)。所有患者入院时、手术当天、术后1和3个月、末次随访均行B超、眼压、最佳矫正视力等检查,比较两组患者术前眼压、脉络膜脱离高度变化及手术复位率、视力改善情况、眼部并发症等,术后随访时间≥6个月。患者术前视力采用单因素方差分析进行比较,其余正态分布的计数资料采用t检验;计数资料采用卡方检验。 结果: 玻璃体切除术前,曲安奈德组和地塞米松组眼压分别为(8.58±3.83)和(6.70±2.49)mmHg(1 mmHg=0.133 kPa)(t=2.032),脉络膜脱离高度分别为0.90(0.00,3.84)和4.03(1.05,5.38)mm(Z=-2.569),差异均有统计学意义(P<0.05)。曲安奈德组患者手术复位率为95.7%(22/23),与地塞米松组的76.0%(19/25)相比,差异无统计学意义(χ(2)=2.304,P=0.129)。末次随访时曲安奈德组视力为0.91±0.54,优于地塞米松组的1.25±0.62(t=-2.034,P=0.048)。术后1和3个月时,曲安奈德组高眼压发生率较高(χ(2)=2.304,5.648;P<0.05),末次随访时差异无统计学意义(χ(2)=0.006,P=0.941)。 结论: 后Tenon囊下注射曲安奈德可提高眼压,降低脉络膜脱离高度,改善脉络膜脱离型视网膜脱离患者23 G玻璃体切除术后的视力预后,但可能会引起术后高眼压。(中华眼科杂志,2018,54:252-257).
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
意林完成签到,获得积分20
1秒前
3秒前
4秒前
田様应助懒洋洋采纳,获得10
5秒前
5秒前
舒适的冰凡完成签到,获得积分10
7秒前
上官发布了新的文献求助10
9秒前
9秒前
9秒前
不会吹口哨完成签到,获得积分10
10秒前
钙离子发布了新的文献求助10
10秒前
英俊的铭应助澡雪采纳,获得10
12秒前
稗子发布了新的文献求助10
13秒前
HeJiangle发布了新的文献求助10
13秒前
顾矜应助默默书竹采纳,获得10
15秒前
比巴卜发布了新的文献求助10
15秒前
CC发布了新的文献求助10
16秒前
夕夕口口完成签到,获得积分10
16秒前
1111应助AHA采纳,获得20
18秒前
牛虻发布了新的文献求助10
21秒前
orixero应助山语采纳,获得10
21秒前
21秒前
Master完成签到 ,获得积分10
22秒前
22秒前
月儿完成签到 ,获得积分10
23秒前
1177发布了新的文献求助10
23秒前
勤奋凝安完成签到,获得积分20
23秒前
量子星尘发布了新的文献求助10
25秒前
25秒前
26秒前
27秒前
auggy发布了新的文献求助10
27秒前
27秒前
默默书竹发布了新的文献求助10
27秒前
30秒前
英俊的铭应助Picky采纳,获得10
30秒前
科研怪咖小白完成签到,获得积分10
30秒前
WQ发布了新的文献求助10
30秒前
30秒前
可爱的函函应助钙离子采纳,获得10
32秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975836
求助须知:如何正确求助?哪些是违规求助? 3520174
关于积分的说明 11201364
捐赠科研通 3256576
什么是DOI,文献DOI怎么找? 1798362
邀请新用户注册赠送积分活动 877539
科研通“疑难数据库(出版商)”最低求助积分说明 806426