Polyoxometalate-Based Metal–Organic Frameworks with Both Proton Acid and Multioxidative Active Sites: Highly Efficient Catalytic Synthesis of Quinazolinones

Quinazolinone derivatives are an important class of pharmaceutical and pesticide intermediates, which are generally synthesized starting with the condensation reaction between aldehydes and 2-aminobenzamide to obtain corresponding intermediates and then oxidized to obtain the products. Although some catalysts have been developed currently for the synthesis of quinazolinone derivatives, their catalytic efficiency is relatively low because only the oxidative catalytic sites of the catalyst have been focused on. Herein, we synthesized three new polyoxometalate-based metal-organic frameworks, [Cu