心脏毒性
诱导多能干细胞
药理学
药品
医学
干细胞
人诱导多能干细胞
药物毒性
心肌细胞
毒性
生物
内科学
细胞生物学
胚胎干细胞
生物化学
基因
作者
Maedeh Mozneb,Amelia Jenkins,Samuel Sances,Stephany Pohlman,Michael J. Workman,Dylan West,Briana N. Ondatje,Kareem El-Ghazawi,Amanda Woodbury,Veronica J. Garcia,Shachi Patel,Madelyn Arzt,Felipe Segato Dezem,Alex Laperle,V. Alexandra Moser,Ritchie Ho,Nur Yucer,Jasmine Plummer,Robert J. Barrett,Clive N. Svendsen,Arun Sharma
出处
期刊：Lab on a Chip
[The Royal Society of Chemistry]
日期：2024-01-01
卷期号：24 (4): 869-881
被引量：4
摘要
Cardiovascular toxicity causes adverse drug reactions and may lead to drug removal from the pharmaceutical market. We have developed a cardiac organ-chip using pluripotent stem cells to enhance cell maturity and model drug cardiotoxicity.
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