多糖
纳米技术
药物输送
医学
计算生物学
生物技术
生物
材料科学
生物化学
作者
Amanda Silva,Didier Letourneur,Cédric Chauvierre
出处
期刊:Theranostics
[Ivyspring International Publisher]
日期:2014-01-01
卷期号:4 (6): 579-591
被引量:46
摘要
Natural polysaccharides have received a lot of attention in the biomedical field. Indeed, sources of polysaccharides, extracted or produced from plants, bacteria, fungi or algae, are diverse and renewable. Moreover, recent progresses in polysaccharide chemistry and nanotechnologies allow elaborating new dedicated nanosystems. Polysaccharide-based nanosystems may be designed for interacting in several biological processes. In particular, the atherothrombotic pathology is highly concerned by polysaccharide-mediated recognition. Atherothrombotic diseases, regardless of the anatomical localization, remain the main causes of morbidity and mortality in the industrialized world. This review intends to provide an overview on polysaccharide-based nanosystems as drug delivery systems and targeted contrast agents for molecular imaging with an emphasis on the treatment and imaging of cardiovascular pathologies.
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