生物传感器
表面等离子共振
纳米技术
材料科学
分析物
生物分析
化学
纳米颗粒
色谱法
作者
Pavel Damborský,Juraj Švitel,Jaroslav Katrlı́k
出处
期刊:Essays in Biochemistry
[Portland Press]
日期:2016-06-30
卷期号:60 (1): 91-100
被引量:696
摘要
Optical biosensors represent the most common type of biosensor. Here we provide a brief classification, a description of underlying principles of operation and their bioanalytical applications. The main focus is placed on the most widely used optical biosensors which are surface plasmon resonance (SPR)-based biosensors including SPR imaging and localized SPR. In addition, other optical biosensor systems are described, such as evanescent wave fluorescence and bioluminescent optical fibre biosensors, as well as interferometric, ellipsometric and reflectometric interference spectroscopy and surface-enhanced Raman scattering biosensors. The optical biosensors discussed here allow the sensitive and selective detection of a wide range of analytes including viruses, toxins, drugs, antibodies, tumour biomarkers and tumour cells.
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