PD-L1 Immunohistochemistry in Gastric Cancer: Comparison of Combined Positive Score and Tumor Area Positivity Across 28-8, 22C3, and SP263 Assays
免疫组织化学
癌症
医学
内科学
肿瘤科
作者
Samuel J. Klempner,Eric S Cowden,Samuel Cytryn,Matteo Fassan,Hisato Kawakami,Hideaki Shimada,Laura H. Tang,Daniel‐Christoph Wagner,Yasushi Yatabe,Alexander Savchenko,Jennifer Salcius,Dorhyun Johng,Jing Chen,G. Montenegro,Markus Moehler
出处
期刊:JCO precision oncology [American Society of Clinical Oncology] 日期:2024-06-01卷期号: (8)被引量:2
The clinical application of PD-L1 immunohistochemistry (IHC) testing is complicated by the availability of multiple IHC assays, scoring algorithms, and cutoffs. This study assessed the analytical comparability of three commercially available PD-L1 assays and two scoring algorithms used to assess PD-L1 status in gastric cancer (GC) samples.