Comparative Effectiveness and Safety of Direct Oral Anticoagulants vs Warfarin Among Nursing Home Residents With Atrial Fibrillation: A Retrospective Cohort Study

Residents of nursing homes are usually excluded from clinical trials, including trials to assess treatments for common conditions such as nonvalvular atrial fibrillation (NVAF). We aimed to quantify the real-world comparative safety and effectiveness of direct-acting oral anticoagulants (DOACs) vs warfarin among nursing home residents with NVAF.