Chondrosarcoma and Chordoma of the Skull Base and Spine: Implication of Tumor Location on Patient Survival

脊索瘤 软骨肉瘤 医学 颅骨 脊柱(分子生物学) 脊柱肿瘤 放射科 外科 生物信息学 生物
作者
Huy Gia Vuong,Ian F. Dunn
出处
期刊:World Neurosurgery [Elsevier]
卷期号:162: e635-e639 被引量:7
标识
DOI:10.1016/j.wneu.2022.03.088
摘要

Chondrosarcoma and chordoma are often grouped together because of their similar anatomic locations, clinical presentations, histopathological and radiological findings, and growth patterns. In the present study, we investigated the clinical and prognostic differences of chondrosarcomas and chordomas of the skull base and spine.We accessed the Surveillance, Epidemiology, and End Results database to search for patients from 2000 to 2018 with chondrosarcomas and chordomas of the skull base and spine for inclusion in the present study.We included 1346 and 1536 cases of chondrosarcoma and chordoma for analysis, respectively. Chondrosarcomas of the cranial base and spine were seen in younger patients and were associated with a larger tumor size compared with chordomas. Among the tumors of the skull base, chondrosarcomas were more common in women, with a male predominance found for chordomas. We also observed a male predilection for both spinal chondrosarcomas and chordomas. Distinct metastatic patterns were found for chondrosarcomas versus chordomas, and spinal chondrosarcomas showed a greater risk of distant metastases at presentation compared with spinal chordomas. Cranial base chondrosarcomas were associated with superior outcomes compared with chordomas. However, we demonstrated an opposite survival pattern for spinal chondrosarcomas and chordomas.Chondrosarcomas and chordomas have divergent clinical manifestations and prognoses depending on the anatomic location.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
ElbingX发布了新的文献求助20
刚刚
noyyet完成签到,获得积分10
刚刚
2秒前
2秒前
3秒前
笑点低的小刺猬完成签到,获得积分10
3秒前
4秒前
大模型应助呆萌的源智采纳,获得10
4秒前
轻松半邪发布了新的文献求助10
4秒前
5秒前
5秒前
5秒前
加菲丰丰应助梦璃采纳,获得20
5秒前
王小茗发布了新的文献求助10
5秒前
6秒前
我是老大应助章章采纳,获得10
6秒前
小椰关注了科研通微信公众号
6秒前
6秒前
科研通AI2S应助秋子采纳,获得10
7秒前
景代丝完成签到,获得积分10
9秒前
完美世界应助ZN采纳,获得30
10秒前
糖串串完成签到,获得积分10
10秒前
三新荞应助lyp采纳,获得10
10秒前
Ava应助暴走采纳,获得10
10秒前
顾矜应助称心不尤采纳,获得10
11秒前
呆萌的源智完成签到,获得积分10
13秒前
赘婿应助zhizhi采纳,获得10
13秒前
华仔应助飞飞飞采纳,获得10
14秒前
王小茗完成签到,获得积分10
14秒前
15秒前
小蘑菇应助hello采纳,获得10
18秒前
安静的千易应助喜悦夏之采纳,获得10
21秒前
小椰发布了新的文献求助10
21秒前
21秒前
乐乐应助grandthief采纳,获得10
21秒前
欧阳发布了新的文献求助10
21秒前
21秒前
科研通AI2S应助蝉鸣采纳,获得10
22秒前
22秒前
三新荞应助明亮的代桃采纳,获得200
23秒前
高分求助中
歯科矯正学 第7版(或第5版) 1004
Smart but Scattered: The Revolutionary Executive Skills Approach to Helping Kids Reach Their Potential (第二版) 1000
Semiconductor Process Reliability in Practice 720
GROUP-THEORY AND POLARIZATION ALGEBRA 500
Mesopotamian divination texts : conversing with the gods : sources from the first millennium BCE 500
Days of Transition. The Parsi Death Rituals(2011) 500
The Heath Anthology of American Literature: Early Nineteenth Century 1800 - 1865 Vol. B 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3228538
求助须知:如何正确求助?哪些是违规求助? 2876357
关于积分的说明 8194668
捐赠科研通 2543440
什么是DOI,文献DOI怎么找? 1373770
科研通“疑难数据库(出版商)”最低求助积分说明 646833
邀请新用户注册赠送积分活动 621413