医学
脂肪性肝炎
组织病理学
肝活检
脂肪变性
肝硬化
酒精性肝炎
脂肪肝
肝损伤
胆汁淤积
肝病
酒精性肝病
病理
胃肠病学
肝炎
内科学
非酒精性脂肪肝
活检
疾病
标识
DOI:10.1016/j.cld.2018.09.001
摘要
Excessive alcohol consumption can lead to a spectrum of liver histopathology, including steatosis, steatohepatitis, foamy degeneration, fatty liver with cholestasis, and cirrhosis. Although variability in sampling and pathologist interpretation are of some concern, liver biopsy remains the gold standard for distinguishing between steatohepatitis and noninflammatory histologic patterns of injury that can also cause the clinical syndrome of alcohol-related hepatitis. Liver biopsy is not routinely recommended to ascertain a diagnosis of alcohol-related liver disease in patients with an uncertain alcohol history, because the histologic features of alcohol-related liver diseases can be found in other diseases, including nonalcoholic steatohepatitis and drug-induced liver injury.
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