Mechanoluminescence (ML) is a unique type of luminescence that has shown significant potential in multiple fields, including stress detection, anticounterfeiting, encryption, and light sources. Recent advancements have been made in understanding how molecules aggregate and interact within solid materials, contributing directly to the development and utilization of mechanoluminescent materials. ML crystals are considered intelligent stress sensors due to their in situ, real-time, and nondestructive properties. They have potential applications in inner crack visualization, light sources, and ultrasonic powder recording. ML-based stress sensing has gained attention due to its remote characteristics and distributed response to mechanical stimuli, as well as its potential for stretchability, biocompatibility, and self-powering. This chapter highlights mechanoluminescent materials and their properties, various anticounterfeiting techniques, applications of ML in anticounterfeiting, and the challenges and future prospects.