Clinical Trials, Case Studies, and Oral Care R&D: Inclusivity, Consistency, and Other Atypical Evidence

Evidence-based assessment plays an obvious, growing, and critical role in directly informing clinical decisions in dentistry. The inputs are complex from diverse sources, and outcomes can appreciably influence the research and development process. Emerging trends may indicate the need for assessment of even more complex data. As exemplified by whitening strips development, inclusive, consistent, and atypical evidence may be considered for informed decision making. In addition to the direct applications, such assessment may indirectly support decision making by professional associations, government authorities, and other health care organizations that influence clinical practice behaviors.