离子液体
化学
傅里叶变换红外光谱
相(物质)
烷基
聚合
柱色谱法
亲水作用色谱法
高效液相色谱法
色谱法
化学工程
材料科学
有机化学
催化作用
聚合物
工程类
作者
Tong Zhang,Xiaojing Liang,Licheng Wang,Shuai Wang,Xiaoxiao Liu,Yong Guo
标识
DOI:10.1016/j.cclet.2024.109889
摘要
An ionic liquid assisted hydrogel modified silica was synthesized using a one-pot polymerization and physical coating technique and subsequently applied to mixed-mode liquid chromatography. Analytical techniques, including Fourier transform infrared spectroscopy (FT-IR), x-ray photoelectron spectroscopy (XPS), and elemental analysis, etc., confirmed the successful prepared of this innovative stationary phase. The unique combination of amide, long alkyl chain, and imidazole ring in the hydrogel coating enables the stationary phase to function effectively in hydrophilic/reversed-phase/ion exchange liquid chromatography. Notably, the stationary phase exhibited superior separation performance owing to the synergistic effect of the ionic liquid and hydrogel. This was particularly evident when analyzing various analytes such as organic acids, nucleosides/bases, polycyclic aromatic hydrocarbons (PAHs) and anions. Furthermore, under our operating conditions, an excellent column efficiency of 53642.9 plates/m was achieved for theobromine. In summary, we have proposed a straightforward strategy to enhance the separation performance of hydrogel coatings in liquid chromatography, thereby broadening the potential applications of hydrogels in the field of separation.
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