Patient-reported outcomes between whole-breast plus regional irradiation and whole-breast irradiation only in pN1 breast cancer after breast conserving surgery and taxane-based chemotherapy: A randomized phase 3 clinical trial (KROG 17-01)

The role of regional node irradiation (RNI) with whole-breast irradiation (WBI) in patients with pN1 breast cancer receiving taxane-based adjuvant chemotherapy is not well defined. The KROG 1701 trial, a phase III, multicenter, non-inferiority study, aimed to compare the disease-free survival between WBI+RNI and WBI alone in this patient cohort. Comprehensive patient-reported outcomes (PROs) collected at multiple time points are reported.