Prospective Randomized Phase 2 Trial of Hypofractionated Stereotactic Radiation Therapy of 25 Gy in 5 Fractions Compared With 35 Gy in 5 Fractions in the Reirradiation of Recurrent Glioblastoma

Glioblastoma (GBM) is the most common adult primary brain tumor. Despite optimal initial management, approximately 90% of patients will develop local progression, after which, median survival is 6.2 months1,2.