胃蛋白酶
共价键
化学
共价有机骨架
色谱法
化学工程
材料科学
酶
有机化学
工程类
作者
Jiale Zhang,Xue Liu,Qixuan Mu,Ruijun Li,Yibing Ji
标识
DOI:10.1002/chem.202303827
摘要
The stable Pepsin@covalent organic framework (Pepsin@COF) were constructed base on matching COF pore diameter to pepsin dimension. It exhibits excellent chiral recognition capabilities (e. e. % up to 62.63 %) and potential for enantioseparation. Furthermore, a positive correlation between the immobilized enzyme activity and chiral recognition was revealed, offering insights for the design of biocatalytic nanosystems in chiral separation.
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