已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Construction of Supramolecular Chiral Polyaniline-Gold Nanocomposite as Nanozyme for Enantioselective Catalysis

对映选择合成 聚苯胺 超分子化学 纳米复合材料 催化作用 材料科学 纳米技术 化学 聚合物 有机化学 晶体结构 聚合 复合材料
作者
Ganyin Yuan,Zheng Xi,Chu Wang,Xiaohuan Sun,Jie Han,Rong Guo
出处
期刊:Acta Physico-chimica Sinica [Peking University Press]
卷期号:: 2212061-2212061 被引量:9
标识
DOI:10.3866/pku.whxb202212061
摘要

Abstract: Enantioselective catalysis is ubiquitous in biological organisms and closely related to biological production and metabolism. The design and development of nanozymes with high enantioselectivities are essential for various bio-related applications. Currently, investigations of nanozymes are primarily focused on their catalytic activity. However, the enantioselectivity of nanozymes, a significant feature, has been rarely studied. In view of the few reports related to enantioselective catalysis, nanozymes have mainly been constructed with chiral molecule-modified nanoparticles. Because the selectivity of natural enzymes not only depends on the molecular chirality of chiral species, such as amino acids, but is also closely related to the chiral supramolecular microenvironment generated by the spatial arrangement and folding of proteins, the construction of active chiral substances with chiral supramolecular microenvironment for nanozymes is also an effective way to design nanozymes with excellent enantioselectivities. Additionally, to improve the enantioselectivity, an understanding of the influencing parameters for select factor of chiral nanozymes is essential. Herein, we report the successful construction of nanocomposites composed of supramolecular M-polyaniline (M-PANI) twisted nanoribbons assembled without any chiral molecules, and Au nanoparticles (NPs) of three different sizes (3, 10, and 16 nm). The characterization results from scanning electron microscopy, transmission electron microscopy, UV-Vis absorption spectroscopy, and X-ray photoelectron spectroscopy confirmed the successful fabrication of M-PANI-Au nanocomposites. The evident signals in the circular dichroism spectra of the M-PANI-Au nanocomposites indicated their potential as chiral nanozymes. Considering the catalytic oxidation of chiral R-/S-3,4-dihydroxyphenylalanine (R-/S-DOPA) enantiomers as a model reaction, the three M-PANI supported Au NPs demonstrated higher catalytic selectivity for R-DOPA than for S-DOPA, as confirmed by the kinetic absorption curves, revealing the high potential of M-PANI-Au nanocomposites as enantioselective nanozymes. Interestingly, according to the kinetic assay study, the M-PANI nanocomposite with 3 nm Au NPs had a higher selection factor (2.59) than those of 10 nm Au NPs (1.46) and 16 nm Au NPs (1.58), which could be attributed to the strongest chirality transfer effect from the supramolecular chiral PANI to 3 nm Au NPs. Therefore, chirality transfer from chiral supramolecular scaffolds to nanozymes is a key factor influencing the enantioselective catalysis and can provide direct guidance for the future design and construction of chiral supramolecular nanozymes with high enantioselectivities.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
niuniu完成签到,获得积分10
刚刚
刚刚
SciGPT应助wukong采纳,获得10
4秒前
5秒前
8秒前
10秒前
12秒前
13秒前
Rain完成签到,获得积分10
13秒前
李爱国应助科研通管家采纳,获得10
15秒前
小马甲应助科研通管家采纳,获得10
15秒前
深情安青应助科研通管家采纳,获得10
15秒前
天天快乐应助科研通管家采纳,获得10
15秒前
彭于晏应助科研通管家采纳,获得10
15秒前
丘比特应助科研通管家采纳,获得10
15秒前
Rondab应助科研通管家采纳,获得30
15秒前
15秒前
FashionBoy应助科研通管家采纳,获得10
15秒前
17秒前
一直向前发布了新的文献求助10
18秒前
18秒前
可爱的函函应助mellow采纳,获得10
18秒前
21秒前
21秒前
TRY发布了新的文献求助10
22秒前
毕业论文三万字完成签到,获得积分10
23秒前
JOY发布了新的文献求助10
25秒前
momo发布了新的文献求助10
25秒前
晗晗有酒窝完成签到,获得积分10
25秒前
缥缈的碧曼完成签到,获得积分10
26秒前
斯文败类应助Steven采纳,获得10
27秒前
28秒前
29秒前
天天快乐应助大喵采纳,获得10
30秒前
mellow发布了新的文献求助10
32秒前
33秒前
33秒前
非也非也6发布了新的文献求助10
33秒前
JOY完成签到,获得积分10
34秒前
猫瓜西完成签到,获得积分10
34秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989811
求助须知:如何正确求助?哪些是违规求助? 3531927
关于积分的说明 11255560
捐赠科研通 3270706
什么是DOI,文献DOI怎么找? 1805035
邀请新用户注册赠送积分活动 882181
科研通“疑难数据库(出版商)”最低求助积分说明 809190