Asymmetric Synthesis of Pyrrolo[1,2-a]indoles via Bifunctional Tertiary Amine Catalyzed [3+2] Annulation of 2-Nitrovinylindoles with Azlactones

The chiral pyrrolo[1,2-a]indole represents a privileged stuctural motif in many natual products and pharmaceutical agents. Herein we developed an efficient [3+2] annulation of 2-nitrovinylindoles with azlactones via the cascade Michael...