化学
羟基化
电子转移
电泳剂
马库斯理论
哈米特方程
反应机理
计算化学
亲电芳香族取代
速率决定步骤
限制
光化学
有机化学
反应速率常数
催化作用
动力学
酶
物理
工程类
机械工程
量子力学
作者
Maaya Asaka,Hiroshi Fujii
摘要
Hydroxylation reactions of aromatic rings are key reactions in various biological and chemical processes. In spite of their significance, no consensus mechanism has been established. Here we performed Marcus plot analysis for aromatic hydroxylation reactions with oxoiron(IV) porphyrin π-cation radical complexes (compound I). Although many recent studies support the mechanism involving direct electrophilic attack of compound I, the slopes of the Marcus plots indicate a significant contribution of an electron transfer process in the rate-limiting step, leading us to propose a new reaction mechanism in which the electron transfer process between an aromatic compound and compound I is in equilibrium in a solvent cage and coupled with the subsequent bond formation process.
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