杜皮鲁玛
封锁
炎症
嗜酸性
医学
免疫学
病理
内科学
受体
特应性皮炎
作者
Cheng‐Chang Yeh,Ming‐Ying Lan,Chen‐Chun Lin,Yu‐Wen Hung,Wan-Ju Huang,Yeong-Lin Lai
出处
期刊:PubMed
日期:2024-09-10
摘要
Dupilumab, an antibody that binds IL-4Rα and inhibits IL-4 and IL-13 signals, has demonstrated efficacy in chronic rhinosinusitis with nasal polyps (CRSwNP) primarily characterized by type 2 inflammation. Current evidence suggests that the rate of improvement in olfactory dysfunction with dupilumab exceeds that of nasal polyp reduction, yet the underlying mechanism remains undisclosed. We hypothesize that dupilumab may initially ameliorate sensorineural olfactory dysfunction.
科研通智能强力驱动
Strongly Powered by AbleSci AI