1,2,5‐Oxadiazole‐Based High‐Energy‐Density Materials: Synthesis and Performance

Abstract This Review covers the synthesis and performance of the most promising 1,2,5‐oxadiazole‐based high‐energy density materials (HEDMs). These materials comprise a 1,2,5‐oxadiazole subunit as a key structural motif linked to various acyclic explosophoric groups or to nitrogen‐rich and nitrogen‐oxygen azoles: 1,2,4‐triazole, tetrazole, 1,2,4‐ and 1,3,4‐oxadiazoles. Energetic alliances of two and more 1,2,5‐oxadiazole rings linked directly or through heteroatom spacers are also presented. Particular attention is devoted to the installation of different explosophores: nitro, nitramino, azo, azoxy, dinitromethyl, trinitroethyl moieties and their combination. Promising environmentally benign energetic materials with high detonation velocity and pressure, and outstanding insensitivity are summarized. Overall, the presented materials may be considered as next‐generation high‐performance energetic materials that are superior to commonly used traditional explosives (TNT, PETN, RDX, HMX).