医学
低血糖
血糖性
糖化血红素
新生儿低血糖
产科
胰岛素
代谢控制分析
怀孕
妊娠期糖尿病
糖尿病
妊娠期
内科学
内分泌学
2型糖尿病
生物
遗传学
作者
Juana A. Flores‐Le Roux,Juan J. Chillarón,Albert Goday,Jaume Puig de Dou,Antonio Payà,María Ángeles López-Vílchez,Juan F. Cano
标识
DOI:10.1016/j.ajog.2010.01.064
摘要
We sought to evaluate intrapartum metabolic control in gestational diabetes mellitus (GDM) patients and maternal factors influencing intrapartum glycemic control and neonatal hypoglycemia risk.A prospective observational study included 129 women with GDM admitted for delivery. Data collected included maternal intrapartum capillary blood glucose (CBG) and ketonemia, use of insulin, and neonatal hypoglycemia.In all, 86% of maternal intrapartum CBG values fell within target range (3.3-7.2 mmol/L) without need for insulin use. There were no cases of maternal hypoglycemia or severe ketosis. Intrapartum CBG >7.2 mmol/L was associated with third-trimester glycated hemoglobin (P = .02) and lack of endocrinologic follow-up (P = .04). Risk of neonatal hypoglycemia was related with pregnancy insulin use compared with dietary control (60.5% vs 29.5%; P = .02).Peripartum metabolic control in GDM patients was achieved without insulin in most cases. Intrapartum glycemic control was related with third-trimester glycated hemoglobin and with no endocrinologic follow-up. Neonatal hypoglycemia was associated with insulin use during pregnancy.
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