Stroke and Amyloid-β Downregulate TREM-2 and Uch-L1 Expression that Synergistically Promote the Inflammatory Response

Neuroinflammation is involved in the pathogenesis of Alzheimer's disease, and the transcription factor NF-κ B is a player in this event. We found here that the ischemic damage alone or in association with Aβ1-42 activates the NF-κ B pathway, induces