作者
Timothy F. Huddy,Yang Hsia,Ryan D. Kibler,Jinwei Xu,Neville P. Bethel,Deepesh Nagarajan,Rachel L. Redler,Philip J. Y. Leung,Connor Weidle,Alexis Courbet,Erin C. Yang,Asim K. Bera,Nicolas Coudray,S. John Calise,Fatima A. Davila-Hernandez,Hannah L. Han,Kenneth D. Carr,Zhe Li,R. Kathryn McHugh,Gabriella Reggiano,Alex Kang,Banumathi Sankaran,Miles Sasha Dickinson,Brian Coventry,TJ Brunette,Yulai Liu,Justas Dauparas,Andrew J. Borst,Damian C. Ekiert,Justin M. Kollman,Gira Bhabha,David Baker
摘要
A wooden house frame consists of many different lumber pieces, but because of the regularity of these building blocks, the structure can be designed using straightforward geometrical principles. The design of multicomponent protein assemblies, in comparison, has been much more complex, largely owing to the irregular shapes of protein structures