Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

生物全基因组关联研究肾病遗传关联遗传学疾病免疫学候选基因基因单核苷酸多态性基因型内科学医学内分泌学糖尿病

作者

Krzysztof Kiryluk,Elena Sánchez,Xu‐jie Zhou,Francesca Zanoni,Lili Liu,Nikol Mladkova,Atlas Khan,Maddalena Marasà,Jun Y. Zhang,Olivia Balderes,Simone Sanna‐Cherchi,Andrew S. Bomback,Pietro A. Canetta,Gerald B. Appel,Jai Radhakrishnan,Hérnan Trimarchi,Ben Sprangers,John C. Lieske,Heather N. Reich,York Pei,Pietro Ravani,Kres̆imir Gales̃ić,Dita Maixnerová,Vladimír Tesař,Bénédicte Stengel,Marie Metzger,Guillaume Canaud,Nicolas Maillard,F Berthoux,Laureline Berthelot,Évangéline Pillebout,Renato C. Monteiro,Raoul D. Nelson,Robert Wyatt,William E. Smoyer,John D. Mahan,Al-Akash Samhar,Guillermo Hidalgo,Alejandro Quiroga,Patricia L. Weng,Raji Sreedharan,David T. Selewski,Keefe Davis,Mahmoud Kallash,Tetyana L. Vasylyeva,Michelle N. Rheault,Aftab S. Chishti,Daniel Ranch,Scott E. Wenderfer,Dmitry Samsonov,Donna Claes,Oleh Akchurin,Dimitrios Goumenos,Μaria Stangou,Judit Nagy,Tibor Kovács,Enrico Fiaccadori,Antonio Amoroso,Cristina Barlassina,Daniele Cusi,Lucia Del Vecchio,Giovanni Giorgio Battaglia,Monica Bodria,Emanuela Boer,Luisa Bono,Giuliano Boscutti,Gianluca Caridi,Francesca Lugani,Gian Marco Ghiggeri,Rosanna Coppo,Licia Peruzzi,Vittoria Esposito,Ciro Esposito,Sandro Feriozzi,Rosaria Polci,Giovanni M. Frascà,Marco Galliani,Maurizio Garozzo,Adele Mitrotti,Loreto Gesualdo,Simona Granata,Gianluigi Zaza,Francesco Londrino,Riccardo Magistroni,Isabella Pisani,Andrea Magnano,Carmelita Marcantoni,Piergiorgio Messa,Renzo Mignani,Ton J. Rabelink,Claudio Ponticelli,Dario Roccatello,Maurizio Salvadori,Erica Salvi,Domenico Santoro,Guido Gembillo,Silvana Savoldi,Donatella Spotti,Pasquale Zamboli,Claudia Izzi,Federico Alberici,Elisa Delbarba,Michał Florczak,Natalia Krata,Krzysztof Mucha,Leszek Pączek,Stanisław Niemczyk,Barbara Moszczuk,Małgorzata Pańczyk-Tomaszewska,Małgorzata Mizerska-Wasiak,Agnieszka Perkowska‐Ptasińska,Teresa Bączkowska,Magdalena Durlik,Krzysztof Pawlaczyk,Przemysław Sikora,Marcin Zaniew,Dorota Kamińska,Magdalena Krajewska,Izabella Kużmiuk-Glembin,Zbigniew Heleniak,Barbara Bułło‐Piontecka,Tomasz Liberek,Alicja Dębska‐Ślizień,Tomasz Hryszko,Anna Materna‐Kiryluk,Monika Miklaszewska,Maria Szczepańska,Katarzyna Dyga,Edyta Machura,Katarzyna Siniewicz‐Luzeńczyk,Monika Pawlak-Bratkowska,Marcin Tkaczyk,Dariusz Runowski,Norbert Kwella,Dorota Drożdz,Ireneusz Habura,Florian Kronenberg,Larisa Prikhodina,David A. van Heel,Bertrand Fontaine,Chris Cotsapas,Cisca Wijmenga,André Franke,Vito Annese,Peter K. Gregersen,Sreeja Parameswaran,Matthew T. Weirauch,Leah C. Kottyan,John B. Harley,Hitoshi Suzuki,Ichiei Narita,Shin Goto,Hajeong Lee,Dong Ki Kim,Yon Su Kim,Jin‐Ho Park,Belong Cho,Murim Choi,Ans Van Wijk,Ana Huerta,Elisabet Ars,Hermann-Josef Gröne,Sigrid Lundberg,Bruno Vogt,Laila‐Yasmin Mani,Yaşar Çalışkan,Jonathan Barratt,Thilini Abeygunaratne,Philip A. Kalra,Daniel P. Gale,Ulf Panzer,Thomas Rauen,Jürgen Floege,Pascal Schlosser,Arif B. Ekici,Kai‐Uwe Eckardt,Nan Chen,Jingyuan Xie,Richard P. Lifton,Ruth J. F. Loos,Eimear E. Kenny,Iuliana Ionita‐Laza,Anna Köttgen,Bruce A. Julian,Jan Novák,Francesco Scolari,Hong Zhang,Ali G. Gharavi

出处

期刊：Nature Genetics [Springer Nature]
日期：2023-06-19 卷期号：55 (7): 1091-1105 被引量：45

链接

nih.govdoi.org

标识

DOI：10.1038/s41588-023-01422-x

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Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

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