药物数据库
药品
药物发现
药物作用
生物信息学
广告
药物基因组学
药理学
药物开发
药物与药物的相互作用
公共化学
药物重新定位
计算生物学
生物信息学
药物靶点
生物
计算机科学
遗传学
基因
作者
David S. Wishart,Craig Knox,An Chi Guo,Dongping Cheng,Savita Shrivastava,Dan Tzur,Bijaya Gautam,Murtaza Hassanali
摘要
DrugBank is a richly annotated resource that combines detailed drug data with comprehensive drug target and drug action information. Since its first release in 2006, DrugBank has been widely used to facilitate in silico drug target discovery, drug design, drug docking or screening, drug metabolism prediction, drug interaction prediction and general pharmaceutical education. The latest version of DrugBank (release 2.0) has been expanded significantly over the previous release. With ∼4900 drug entries, it now contains 60% more FDA-approved small molecule and biotech drugs including 10% more ‘experimental’ drugs. Significantly, more protein target data has also been added to the database, with the latest version of DrugBank containing three times as many non-redundant protein or drug target sequences as before (1565 versus 524). Each DrugCard entry now contains more than 100 data fields with half of the information being devoted to drug/chemical data and the other half devoted to pharmacological, pharmacogenomic and molecular biological data. A number of new data fields, including food–drug interactions, drug–drug interactions and experimental ADME data have been added in response to numerous user requests. DrugBank has also significantly improved the power and simplicity of its structure query and text query searches. DrugBank is available at http://www.drugbank.ca
科研通智能强力驱动
Strongly Powered by AbleSci AI