Box-Behnken设计
Plackett–伯曼设计
响应面法
造粒
数学
材料科学
工艺工程
色谱法
统计
化学
分析化学(期刊)
工程类
出处
期刊:China journal of Chinese materia medica
[China Journal of Chinese Materia Medica]
日期:2015-11-15
标识
DOI:10.4268/cjcmm20152216
摘要
First with the qualified rate of granules as the evaluation index, significant influencing factors were firstly screened by Plackett-Burman design. Then, with the qualified rate and moisture content as the evaluation indexes, significant factors that affect one-step pelletization technology were further optimized by Box-Behnken design; experimental data were imitated by multiple regression and second-order polynomial equation; and response surface method was used for predictive analysis of optimal technology. The best conditions were as follows: inlet air temperature of 85 degrees C, sample introduction speed of 33 r x min(-1), density of concrete 1. 10. One-step pelletization technology of Biqiu granules by Plackett-Burman design and Box-Behnken response surface methodology was stable and feasible with good predictability, which provided reliable basis for the industrialized production of Biqiu granules.
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