Prolonged QT-interval in cirrhosis: is it reversible?

For decades a characteristic cardiovascular pattern has been recognized in patients with end-stage liver disease characterized by low systemic vascular resistance and high cardiac output. This hyperdynamic state seems to affect development of complications and the course of the disease in these patients [1]. Despite a hyperdynamic circulation the physiologic response to strain is abnormal and may lead to overt heart failure after invasive procedures and for example to development of hepatic nephropathy as part of a cardiorenal syndrome [1].