电压依赖性阴离子通道
Uniporter公司
钙
线粒体
兰尼定受体
细胞生物学
化学
线粒体通透性转换孔
生物物理学
T型钙通道
钙信号传导
线粒体膜转运蛋白
线粒体内膜
电压依赖性钙通道
生物化学
生物
程序性细胞死亡
细胞凋亡
胞浆
细菌外膜
酶
有机化学
基因
大肠杆菌
作者
Zhao-Long Xu,Dayong Zhang,Xiaolan He,Yihong Huang,Hongbo Shao
出处
期刊:Current Genomics
[Bentham Science]
日期:2016-03-29
卷期号:17 (3): 215-219
被引量:46
标识
DOI:10.2174/1389202917666160202215748
摘要
To uptake calcium ions of mitochondria is of significant functional connotation for cells, because calcium ions in mitochondria are involved in energy production, regulatory signals transfer, and mitochondrial permeability transition pore opening and even programmed cell death of apoptosis, further playing more roles in plant productivity and quality. Cytoplasmic calcium ions access into outer mitochondrial membrane (OMM) from voltage dependent anion-selective channel (VDAC) and were absorbed into inner mitochondrial membrane (IMM) by mitochondrial calcium uniporter (MCU), rapid mitochondrial calcium uptake (RaM) or mitochondrial ryanodine receptor (mRyR). Although both mitochondria and the mechanisms of calcium transport have been extensively studied, but there are still long-standing or even new challenges. Here we review the history and recent discoveries of the mitochondria calcium ions channel complex involved calcium assimilation, and discuss the role of calcium ions into mitochondria. Keywords: Mitochondria, Channels, Calcium ions uptake, Uniporter.
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