Lipoprotein(a) concentrations and cardiovascular disease in patients with chronic kidney disease: Results from the German Chronic Kidney Disease study
医学
肾脏疾病
疾病
内科学
作者
I Gruber,Barbara Kollerits,Lukas Forer,Silvia Di Maio,Johanna F. Schachtl‐Riess,Azin Kheirkhah,Sebastian Schönherr,Ulla T. Schultheiß,Anna Köttgen,Kai‐Uwe Eckardt,Stefan Coassin,Claudia Lamina,Florian Kronenberg
Lipoprotein(a) (Lp(a)) is a causal, genetically determined risk factor for cardiovascular disease (CVD) in the general population. Patients with chronic kidney disease (CKD) have an increased CVD risk and elevated Lp(a) concentrations. Only a few studies on Lp(a) were performed in persons with mild-to-moderate CKD; none of them used genetic variants to explore potential causal associations.