Antisense oligonucleotides for atherosclerotic disease
寡核苷酸
计算生物学
医学
生物
疾病
病理
生物化学
DNA
作者
Archna Bajaj,Daniel J. Rader
出处
期刊:Nature Medicine [Springer Nature] 日期:2020-04-01卷期号:26 (4): 471-472被引量:3
标识
DOI:10.1038/s41591-020-0835-2
摘要
Novel RNA-targeting antisense therapy is shown to reduce lipoprotein(a) levels in 286 patients with existing atherosclerotic disease by upwards of 80% in a phase 2 clinical trial.