Preparation and Synthetic Applications of 2-Halotryptophan Methyl Esters: Synthesis of Spirotryprostatin B

Spirocyclisierung von N-Acyliminium-Ionen: 2-Halogentryptophanester sind wertvolle Synthesebausteine für die stereokontrollierte Synthese von Spiro[pyrrolidin-3,3′-oxindolen] (siehe Schema). Der Zellzyklus-Inhibitor Spirotryprostatin B ist mit der hier beschriebenen Methode rasch zugänglich. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2004/z460419_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.