紧身衣
光热治疗
红外线的
纳米技术
材料科学
荧光
光学
物理
作者
Yang Liu,Nan Song,Li Chen,Shi Liu,Zhigang Xie
标识
DOI:10.1002/asia.201701727
摘要
The development of robust photothermal agents for near-infrared (NIR) imaging is a great challenge. Herein, we report the design and synthesis of a new photothermal agent, based on the aza-boron-dipyrromethene framework (azaBDP). This compound possessed excellent photostability and high photothermal-conversion efficiency (50 %) under NIR laser irradiation. When the photothermal properties of this compound were utilized for tumor inhibition, stable long-term fluorescence was observed in living animals. Photothermal treatment efficiently suppressed tumor growth, as evidenced by in vitro and in vivo experiments. Furthermore, NIR emission could be detected by using an imaging system and therapeutic self-monitoring was achieved by using NIR imaging.
科研通智能强力驱动
Strongly Powered by AbleSci AI