医学
黑色素瘤
背
脚(韵律)
皮肤病科
外科
解剖
语言学
哲学
癌症研究
作者
Alexis M. Ruffolo,Ashwath J. Sampath,Jeffrey H. Kozlow,Michael W. Neumeister
标识
DOI:10.1016/j.cps.2021.05.009
摘要
Melanomas only account for 4% of all dermatologic cancers yet are responsible for 80% of deaths. Notably, melanomas of the hand and foot have a worse prognosis when compared with melanomas of other anatomic regions. Likely this is due to intrinsic biologic characteristics, delayed diagnosis, difficult surgical excision due to delicate anatomy, and lack of definitive diagnostic and therapeutic guidelines. The most common locations of melanoma of the hand, in order of decreasing frequency, are subungual area, dorsal surface, and palmar surface. The most common locations of melanoma of the foot are the plantar surface, dorsal surface, and subungual area, in decreasing frequency. Diagnosis of melanoma of the hand and foot can be difficult because the traditional “ABCDE” (asymmetric shape, border, color, diameter, evolution) rules do not apply. Newer acronyms have been proposed in literature including “CUBED” (colored, uncertain, bleeding, enlarged, delayed) and “ABC rule for Subungual Melanoma.” Once diagnosed, treatment is primarily surgical excision and reconstruction. The goal for the surgeon is to maintain the function and anatomy of the hand or foot.
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