Critical role of farnesoid X receptor for hepatocellular carcinoma cell proliferation

Journal Article Critical role of farnesoid X receptor for hepatocellular carcinoma cell proliferation Get access Tomofumi Fujino, Tomofumi Fujino * 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan *Tomofumi Fujino, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan. Tel: +81 42 676 4513, Fax: +81 42 676 4508, email: tfujino@ps.toyaku.ac.jp Search for other works by this author on: Oxford Academic PubMed Google Scholar Airi Takeuchi, Airi Takeuchi 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Akiko Maruko-Ohtake, Akiko Maruko-Ohtake 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Yosuke Ohtake, Yosuke Ohtake 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Junichi Satoh, Junichi Satoh 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Tomonori Kobayashi, Tomonori Kobayashi 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Toshiaki Tanaka, Toshiaki Tanaka 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Haruka Ito, Haruka Ito 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Ryosuke Sakamaki, Ryosuke Sakamaki 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Ryo Kashimura, Ryo Kashimura 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar ... Show more Ken Ando, Ken Ando 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Tomoko Nishimaki-Mogami, Tomoko Nishimaki-Mogami 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Yasuhito Ohkubo, Yasuhito Ohkubo 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Naomi Kitamura, Naomi Kitamura 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Ryuichiro Sato, Ryuichiro Sato 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Kiyomi Kikugawa, Kiyomi Kikugawa 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Makio Hayakawa Makio Hayakawa 1School of Pharmacy, Tokyo University of Pharmacy and Life Science; 2Department of Radiopharmacy, Tohoku Pharmaceutical University; 3Department of Biological Sciences, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology; 4The National Institute of Health Sciences; and 5Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Biochemistry, Volume 152, Issue 6, December 2012, Pages 577–586, https://doi.org/10.1093/jb/mvs101 Published: 10 September 2012 Article history Received: 01 August 2012 Accepted: 20 August 2012 Published: 10 September 2012