上瘾
增食欲素
睡眠(系统调用)
心理学
睡眠剥夺
睡眠限制
多巴胺能
嗜睡症
神经科学
非快速眼动睡眠
精神科
多巴胺
昼夜节律
医学
内科学
神经学
神经肽
脑电图
受体
操作系统
计算机科学
作者
Luis Angel López-Muciño,Fabio García‐García,Jonathan Cueto‐Escobedo,Mario Eduardo Acosta-Hernández,Arturo Venebra-Muñoz,Juan Carlos Rodríguez‐Alba
标识
DOI:10.1016/j.neubiorev.2022.104832
摘要
Reducing sleep hours is a risk factor for developing cardiovascular, metabolic, and psychiatric disorders. Furthermore, previous studies have shown that reduction in sleep time is a factor that favors relapse in addicted patients. Additionally, animal models have demonstrated that both sleep restriction and sleep deprivation increase the preference for alcohol, methylphenidate, and the self-administration of cocaine. Therefore, the present review discusses current knowledge about the influence of sleep hours reduction on addictivebehaviors; likewise, we discuss the neuronal basis underlying the sleep reduction-addiction relationship, like the role of the orexin and dopaminergic system and neuronal plasticity (i.e., delta FosB expression). Potentially, chronic sleep restriction could increase brain vulnerability and promote addictive behavior.
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